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diabetes

Glucophage XR

metformin extended release

By Bristol-Myers Squibb

What is this medication for?

Metformin extended release belongs to a class of medications called oral hypoglycemics (medications that lower blood sugar). It is used for the control of blood glucose (blood sugar) by people with type 2 diabetes. It is used when diet, exercise, and weight reduction have not lowered blood glucose well enough on their own. Metformin extended release works by reducing the amount of glucose made by the liver and by making it easier for glucose to enter the tissues of the body.

Your doctor may have suggested this medication for conditions other than those listed here. As well, some forms of this medication may not be used for all of the conditions discussed here. If you are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

What form(s) does this medication come in?

Glucophage XR® is available as:

  • extended release tablets
    • 500 mg
    • 750 mg
Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.

How should I use this medication?

The usual starting dose of metformin extended release is 500 mg once daily with the evening meal. Dosage increases should be made in increments of 500 mg weekly, up to a maximum of 2,000 mg once daily with the evening meal.

Tablets should be swallowed whole with water or other liquids. Do not crush, chew, or split the tablets.

Metformin extended release may be taken alone or with other medications that reduce blood glucose by people 17 years of age and older. To ensure the medication is working well, monitor your blood glucose on a regular basis as directed by your doctor or diabetes specialist.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Who should NOT take this medication?

Do not take this medication if you:

  • are allergic to metformin extended release or any ingredients of the medication
  • are receiving injections of iodinated contrast materials for radiological studies
  • have acute or chronic metabolic acidosis, including diabetic ketoacidosis
  • have congestive heart failure requiring medication
  • have kidney disease or kidney dysfunction
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