What is this medication for?
Tolbutamide belongs to the class of medications called oral hypoglycemics. It is also known as a sulfonylurea agent. It is used along with diet to improve control of blood glucose (sugar) for people with type 2 diabetes. It is used when diet, exercise, and weight reduction have not been found to control blood glucose well enough on their own.
Tolbutamide works by increasing the amount of insulin (a hormone produced by the pancreas that allows sugar to enter into cells where it is needed for energy) released by the pancreas and by helping the body to use insulin more efficiently.
Having good control of blood glucose levels is the key to reducing the risk of diabetes complications (e.g., kidney disease, eye problems, nerve problems).
Your doctor may have suggested this medication for conditions other than those listed here. As well, some forms of this medication may not be used for all of the conditions discussed here. If you are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
What form(s) does this medication come in?
Tolbutamide by Watson Pharmaceuticals is available as:
Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.
How should I use this medication?
The recommended adult dose of tolbutamide ranges from 250 mg to 3,000 mg daily depending on the need according to blood glucose tests and as prescribed by your doctor. This medication can be taken either in the morning or in divided doses through the day.
It is very important to monitor blood sugar levels closely, especially when increasing and decreasing doses of medication or when exercise levels or weight changes occur. Your doctor or diabetes educator will instruct you on the best use of a glucose monitor.
Many things can affect the dose of medication that a person needs, such as
body weight, other medical conditions, and other medications. If your doctor
has recommended a dose different from the ones listed here, do not change
the way that you are taking the medication without consulting your doctor.
It is important to take this medication exactly as
prescribed by your doctor. If you miss a dose, take it as soon
as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Low blood sugar (hypoglycemia) is an important
concern if too much of this medication is taken for your circumstances. Ask
your doctor or diabetes educator what you should do when you are not going to
be eating for a long period of time or when you are going to be exercising more
than usual. Do not take a double dose to make up for a missed one.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Who should NOT take this medication?
Do not take this medication if you:
- are allergic to tolbutamide or any ingredients of the medication
- have diabetic ketoacidosis
- have type 1 diabetes (you should always be using insulin)